NEUPC is seeking to award a Framework Agreement for the provision of Molecular Biology Research Services. The Framework Agreement has been split into 4 lots as follows:

Lot 1: sequencing Services

Lot 2: genotyping Services

Lot 3: DNA/RNA Extraction Services

Lot 4: oligonucleotides

The requirement for Next Generation sequencing services will provide a complete workflow from cells to data which could include, but is not limited to, the following types of services:

(i) Whole Genome Sequencing;

(ii) Exome Sequencing;

(iii) RNA-Sequencing;

(iv) RNA analysis;

(v) Targeted Sequencing;

(vi) 16s Microbial Sequencing;

(vii) Small RNA Sequencing;

(viii) Gene Sequencing;

(ix) Methylation Sequencing;

(x) HiC library preparation;

(xi) Long-mate pair preparation;

(xii) Optical Mapping;

(xiii) Bioinformatic Services — Data Analysis, Interpretation and Reporting of sequencing services;

(xiv) ChiP-Seq;

Alternative solutions or processes that can achieve the same outcomes are/will be covered under this framework agreement.

The requirement for Sanger sequencing services will provide a complete workflow from cells to data which could include, but is not limited to, the following types of services:

(i) Sanger sequencing;

(ii) PCR Amplification;

(iii) Cloning;

(iv) Bioinformatic Services — Data Analysis, Interpretation and Reporting of sequencing services.

Alternative solutions or processes that can achieve the same outcomes are/will be covered under this framework agreement.

Lot 3: Genotyping Services

The requirement for genotyping services will provide a complete workflow from cells to data which will include, but is not limited to, the following type of services:

(i) Genotyping of Single Nucleotide Polymorphysm (SNP);

(ii) Genotyping of simple sequence repeat (SSR);

(iii) Genotyping by Microsatellite;

(iv) Any other Genotyping services;

(v) All-inclusive genotyping service;

(vi) Array-based genotyping;

(vii) Bioinformatic Services — Data Analysis, Interpretation and Reporting of genotyping services.

Alternative solutions or processes that can achieve the same outcomes are/will be covered under this framework agreement.

The requirement for DNA/RNA extraction services will provide a complete workflow from cells to data which will include, but is not limited to, extraction from the following sources:

(i) whole blood;

(ii) Saliva;

(iii) FTA paper;

(iv) Buccal swabs;

(v) Mammalian cell lines/primary cells (cell pellets);

(vi) Plant and animal tissue;

(vii) FFPE tissue;

(viii) Bacteria;

(ix) Any other source as requested;

(x) Extracted DNA/RNA must be suitable for use in various downstream applications as requested;

(xi) Bioinformatic Services — Data Analysis, Interpretation & Reporting of extraction services

Alternative solutions or processes that can achieve the same outcomes are/will be covered under this framework agreement.

The requirement for the provision of Oligonucleotides to support basic biological research and applied fields such as diagnostic, biotechnology, forensic biology, biological systematic and varied research projects undertaken by individual Member Institutions will include, but is not limited to, the following:

(i) Standard Oligo synthesis;

(ii) Oligo purification;

(iii) Custom RNA synthesis;

(iv) Molecular beacons;

(v) XS Probes;

(vi) Internal Degenerated bases;

(vii) Full QC analysis of the Oligo sequences provided.

Alternative solutions or processes that can achieve the same outcomes are/will be covered under this framework agreement