The MRL has an advanced metabolic phenotyping facility, the Disease Model Core which will be replacing one of its in-house built indirect calorimeters for the system outlined below in the tender. Through this Core the Department phenotypes a wide range of murine models of metabolic disease, and as such needs a low maintenance, highly adaptable, dependable calorimeter that can serve its needs.

The University of Cambridge Metabolic Research Laboratories (MRL) and its embedded MRC Metabolic Disease Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.

The MRL brings together outstanding scientific and clinical researchers to create an international centre of excellence for research into metabolic disease. Each group is led by a principal investigator who, along with their group members, is also a member of a “home” University department. Between them, groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, as well as experimental medicine and clinical trials.

The MRL has an advanced metabolic phenotyping facility, the Disease Model Core which will be replacing one of its in-house built indirect calorimeters for the system outlined below in the tender. Through this Core the Department phenotypes a wide range of murine models of metabolic disease, and as such needs a low maintenance, highly adaptable, dependable calorimeter that can serve its needs.