Supply of "reagents and systems for Oncology and Onco-Hematology diagnostics" (PCR, PCR Nested, Real Time PCR, NGS methods) for the U.O.C of Anatomy and Pathological Histology of the ULSS 2 Treviso brand, for the period of 36 months.

The supply consists of 4 lots:

Lots no. 1 and no. 3 including reagents, consumables and equipment;

Lots no. 2 and no. 4 including reagents and consumables.

SINTEL ID 165162490.

Complete system for molecular analysis (see tender documentation):

REF. A - Reagents for identification and quantification

REF. B - Reagents for identification and quantification

REF. C - Reagents for the identification of mutations A,B,D of the NPM1 gene

REF. D - Reagents for identification and quantification of the WT1 gene exon 1 and 2

REF. E - Reagents for identification and quantification of mutation A of the NPM1 gene

REF. F - Reagents for the identification and quantification of B and D mutations in the NPM1 gene

REF. G - Reagents for identification and quantification of transcript derived from t(8;21)AML1-ETO

REF. H - Reagents for identification and quantification of transcripts (A, D and E) derived from t(16;16)inv16 CBFB/MYH11

REF. I - Reagents for identification and quantification of transcripts bcr1, bcr2, bcr3 derived from t(15;17)PML/RARA

REF. L - European certification path for the molecular analysis of LAM in adults

REF. M - Instrument for quantitative PCR amplification (Real Time) in plate of 96 wells

Reagents for the quantitative analysis of the V617 mutation of the JAK gene and for the qualitative analysis of the W515L/K mutations of the MPL gene by Allele Specific Real Time PCR method

REF. A - Reagents for the identification and quantification of the V617F mutation of the JAK2 gene and internal extraction controls

REF. B - Reagents for the identification of W515L/K mutations in the MPL gene and internal extraction controls

Complete system for molecular analysis (see tender documentation)

REF. A - Reagents for the analysis of the main mutations on codons 12,13,59,61,117,146 of the KRAS gene

REF. B - Reagents for the analysis of major mutations on codon 600 of the BRAF gene

REF. C - Reagents for the analysis of major mutations on codons 12,13,59,61,117,146 of the NRAS gene

REF. D - Reagents for the analysis of major mutations on codons 18,19,20,21, of the EGFR gene

REF. E - Reagents for the analysis of the main resistance mutations T790M and C797S of the EGFR gene

REF. F - Reagents for the analysis of major mutations on codons 132 of the IDH1 gene and 172 of the IDH2 gene

REF. G - Reagents for the analysis of the main mutations on codons 420,542,545,546,1047 of the PIK3CA gene

REF. H - Reagents for the analysis of mutations in the DPYD gene

REF. I - Reagents for the analysis of mutations in the UGT1A1 gene

REF. L - Reagents for the analysis of the microsatellite instability study (MSI) RealTime PCR method and denaturing curve analysis

REF. M - Reagents for the analysis of the microsatellite instability study (MSI) PCR method and fragment analysis

REF. N - Reagents for the analysis of MET ALK,ROS, RET and Exon Skipping mergers exon 14

REF. O - Reagents for thyroid rearrangement analysis for RET/PTC, PAX8/PPARG genes

REF. P - Reagents for the identification of NTK1,NTK2, NTK3 gene fusions

REF. Q - Reagents for the identification of high-risk Human Papilloma Virus (HPV) genotypes

REF. R - Strumentazione Real Time PCR

Reagents for mutational analysis of genes by NGS-Next Generation Sequencing- in LAM, MDS MPN in adults and T and B cell lymphomas, data acquisition, interruption and analysis software

REF. A: Reagents for the mutational analysis of genes involved in LAM, MDS and MPN by NGS;

REF. B: Reagents for mutational analysis of genes involved in T and B cell lymphomas by NGS;

REF. C: Data acquisition and interpretation software;

REF D: European certification path for molecular analysis by NGS panel of LAM in adults