The Trust is the cancer centre for North East London and provides a medical and haematological oncology service including bone marrow transplantation. The chemotherapy pharmacy department has a licensed chemotherapy production unit, providing over 45 000 doses of systemic anti-cancer treatments (SACT) per year.
Demand for the provision of SACT has been rising consistently year on year. As such the department has developed a strategy to meet this demand and ensure that patient treatment requirements can be met. This strategy includes maximising efficiency of our existing production capacity by outsourcing doses that can be manufactured externally, to quality standards and that will be safe for the patient.
The outsourced doses will be purchased in the form of both ready made dose banded products and patient specific doses.
The following drugs may be required (not exhaustive and subject to change as new drugs are commissioned).
Patient specific doses of systemic anti-cancer treatments:
— bleomycin infusion,
— bleomycin injection,
— bortezomib injection,
— carboplatin infusion,
— cetuximab infusion,
— cisplatin infusion,
— cyclophosphamide infusion,
— cytarabine injection,
— cytarabine infusion,
— daratumumab infusion,
— docetaxel infusion,
— etoposide infusion,
— fluorouracil infusion in bags and LV2, LV5 and LV10 pumps,
— gemcitabine infusion,
— ifosfamide infusion,
— irinotecan infusion,
— methotrexate infusion,
— methotrexate injection,
— oxaliplatin infusion,
— paclitaxel infusion,
— pembrolizumab infusion,
— pemetrexed infusion,
— trastuzumab infusion (both branded and biosimilar),
— vincristine infusion,
— vincristine injection,
— vinorelbine infusion.
Dose banded:
— bleomycin infusion,
— bortezomib injection,
— carboplatin infusion,
— cisplatin infusion,
— cyclophosphamide infusion,
— docetaxel infusion,
— doxorubicin,
— fluorouracil infusion in 100 ml bags,
— fluorouracil infusion in LV5 pumps,
— gemcitabine infusion,
— irinotecan infusion,
— oxaliplatin infusion,
— paclitaxel infusion,
— pembrolizumab infusion,
— pemetrexed infusion,
— trastuzumab infusion (both branded and biosimilar),
— vincristine infusion,
— vinblastine infusion.