The subject of this publication is the conclusion of non-exclusive agreements on various contrast agents/drug combinations as part of a cross-active open-house procedure, which are prescribed and delivered at the expense of the health insurance companies in Brandenburg in the SSB. As a rule, several active substances of the same indication are grouped into 15 specialist groups. For more information, see Appendix 11 to the RFQ. Contrast agents of any future contracting partner can be ordered by the contracting doctors who are informed about these economic sources of supply during the contract period due to the profitability requirement; they are considered to be economically viable. Contract doctors are obliged to meet their demand for contrast agents from a specialist group with the products of the contractual partner or one of the contracting partners.

Name: Ionic iodine-containing highly osmolar, water-soluble nephrotropic X-ray contrast media.

Use: orally and/or rectally. More possible

Application areas:

- X-ray diagnosis of the gastrointestinal tract, especially if the use of barium sulfate is undesirable or contraindicated and/or

- for X-ray imaging of the large intestine and/or

- for examination or delimitation of the gastrointestinal tract during computer tomography.

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration: all concentrations of an active ingredient must be offered.

Pack size: all approved pack sizes of an active substance must be offered.

Special feature: The areas of application can also be covered with several products from one provider.

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular linear contrast media for MRI with renal excretion and partial biliary excretion

Application: intravenous. More possible

Application areas:

- MRI of liver

NSF risk: medium NSF risk

Dosage form: all approved dosage forms of an active ingredient

Concentration: all concentrations possible

Pack size: all approved pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic combines extracellular and hepatobiliary linear contrast agents for MRI (excretion 50-50)

Application: Intravenous use. More possible

Application areas:

- MRI of liver

NSF risk: medium NSF risk class

Dosage form: all dosage forms of the active ingredient

Concentration: all concentrations possible

Pack size: all pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Description: Contrast media containing barium sulphate

Application: Oral and/or intestinal and/or rectal use

application areas

- CT and/or X-ray visualization of parts of the digestive tract and/or the entire digestive tract, further possible

Dosage form: all dosage forms of the active ingredient

Concentrations: all concentrations possible

Pack size: all pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, others possible

Active ingredients / combinations (ATC): Phospholipid microspheres, containing perflutren (V08DA04)

Dosage form: all dosage forms

Concentration: all concentrations possible

Pack size: all pack sizes

Further information can be found in Appendix 11 to

Request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, others possible

Active ingredients / combinations (ATC): Albumin microspheres, containing perfluoride

(V08DA01)

Dosage form: all dosage forms

Concentration: All concentrations

Pack size: all pack sizes

Further information can be found in Appendix 11 to the request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, Doppler sonography of the liver

And chest, ultrasound of the urinary tract

Active ingredients / combinations (ATC): Sulfur hexafluoride (V08DA05)

Dosage form: all dosage forms

Concentration: All concentrations

Pack size: all pack sizes

Further information can be found in Appendix 11 to the request for quotation.

Name: Ionic iodine-containing highly osmolar water-soluble nephrotropic X-ray contrast media.

Application: instillation. More possible.

Application areas:

- retrograde urography,

- mictioncystouretrography

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration: all concentrations of an active substance must be offered

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 to the request for quotation.

Name: Non-ionic iodine monomeric low osmolar water soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous. More possible

application areas

- urography,

- phlebography, arteriography, angiography,

- angiocardiography,

- digital subtraction angiography,

- CT contrast enhancement

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentrations: must be offered cumulatively

1. 300 mg/ ml - 320 mg/ml

2. 350 mg/ml - 400 mg/ml (all concentrations of an active substance must be offered, all areas of application must be covered at least together)

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 of the request for offer.

Description: Non-ionic iodine-containing monomeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intrathecal. More possible

Application areas:

- cervical, thoracic and lumbar myelography and radiculography,

- CT myelography

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration:

200 mg/ ml - 300 mg/ml (all concentrations of an active substance must be offered)

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 to the request for quotation.

Description: Non-ionic iodine-containing monomeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous and intracavity. More possible

Application areas:

- urography,

- phlebography,

- CT contrast enhancement,

- digital substration angiography

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration: 150mg/ml-250 mg/ml, all concentrations of an active substance must be offered

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 to the request for quotation.

Name: Non-ionic iodine-containing dimer low osmolar water soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous. More possible

Application areas:

- cerebral angiography, abdominal angiography, peripheral arteriography, venography

- urography,

- Contrast enhancement in computer tomography (CT)

Concentrations: must be offered cumulatively:

1.270 mg / ml

2. 320 mg/ml

(all concentrations of an active ingredient must be offered, at least all areas of application must be covered)

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular linear contrast media for MRI

Application: Intra-articular application

Application areas:

- direct magnetic resonance arthrography

NSF risk: high NSF risk class

Dosage form: all dosage forms of the active ingredient for this indication

Concentration: 0.002 mmol / ml

Pack size: all pack sizes of the active ingredient for this indication

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular macrocyclic contrast media for MRI

Application: intravenous. More possible

NSF risk: low NSF risk

Application areas:

- cranial and spinal magnetic resonance imaging,

- MRI of other organs

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration: all concentrations of an active substance must be offered

Pack size: all approved pack sizes of an active substance must be offered

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular macrocyclic contrast agents for MRI

Application: Intra-articular application

Applications: direct magnetic resonance arthrography

NSF risk: low NSF risk class

Dosage form: all dosage forms of the active ingredient for this indication

Concentration: 0.0025 mmol / ml

Pack size: all pack sizes of the active ingredient for this indication

Further information can be found in Appendix 11 to the request for quotation.