The subject of this publication is the conclusion of non-exclusive agreements on various contrast agent active ingredients / active ingredient combinations within the framework of a cross-active ingredient open-house procedure, which are prescribed and dispensed in the SSB at the expense of the health insurance companies in Mecklenburg-Western Pomerania. As a rule, several active ingredients for the same indication are grouped into 15 specialist groups. Further details can be found in Appendix 11 to the request for quotation. Contrast media of each future contractual partner can be ordered for a specialty group during the contract period due to the economic efficiency requirement by the contract physicians, who are informed about these economic sources of supply; they are considered economical. Contract doctors are obliged to meet their need for contrast media from a specialist group with the products of the contract partner or one of the contract partners. There is no substitution by the AOK.

Name: Ionic iodine-containing highly osmolar, water-soluble nephrotropic X-ray contrast media.

Application: oral and / or rectal. More possible

Application areas:

- X-ray diagnostics of the gastrointestinal tract, especially if the use of barium sulfate is undesirable or contraindicated and / or

- for X-ray imaging of the large intestine and / or

- for examining or delimiting the gastrointestinal tract in computer tomography.

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentration: all concentrations of an active ingredient must be offered.

Pack size: all approved pack sizes of an active substance must be offered.

Special feature: The areas of application can also be covered with several products from one provider.

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular linear contrast media for MRI with renal excretion and partial biliary excretion

Application: intravenous. More possible

Application areas:

- MRI of the liver.

NSF risk: medium NSF risk

Dosage form: all approved dosage forms of an active ingredient

Concentration: all concentrations possible

Pack size: all approved pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic combined extracellular and hepatobiliary linear contrast media for MRI (excretion 50-50)

Application: Intravenous use. More possible

Application areas:

- MRI of the liver.

NSF risk: medium NSF risk class

Dosage form: all dosage forms of the active ingredient

Concentration: all concentrations possible

Pack size: all pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Description: Contrast media containing barium sulphate

Application: Oral and / or intestinal and / or rectal use

application areas

- Representation of parts of the digestive tract and / or the entire digestive tract by CT and / or X-ray, others possible

Dosage form: all dosage forms of the active ingredient

Concentrations: all concentrations possible

Pack size: all pack sizes of the active ingredient

Further information can be found in Appendix 11 to the request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, others possible

Active ingredients / combinations (ATC): Phospholipid microspheres, containing perflutren (V08DA04)

Dosage form: all dosage forms

Concentration: all concentrations possible

Pack size: all pack sizes

Further information can be found in Appendix 11 to

Request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, others possible

Active ingredients / combinations (ATC): Albumin microspheres, containing perfluoride

(V08DA01)

Dosage form: all dosage forms

Concentration: All concentrations

Pack size: all pack sizes

Further information can be found in Appendix 11 to the request for quotation.

Name: ultrasound contrast medium

Application: Intravenous use

Areas of application: echocardiography, Doppler sonography of the liver

And chest, ultrasound of the urinary tract

Active ingredients / combinations (ATC): Sulfur hexafluoride (V08DA05)

Dosage form: all dosage forms

Concentration: All concentrations

Pack size: all pack sizes

Further information can be found in Appendix 11 to the request for quotation.

Name: Ionic iodine-containing highly osmolar, water-soluble nephrotropic X-ray contrast media.

Application: instillation. More possible.

Application areas:

- retrograde urography,

- Micturition cystouretrography

Dosage form: all approved dosage forms of an active ingredient must be offered.

Concentration: all concentrations of an active ingredient must be offered.

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 to the request for quotation.

Description: Non-ionic iodine-containing monomeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous. More possible

application areas

- urography,

- venography, arteriography, angiography,

- angiocardiography,

- digital subtraction angiography,

- CT contrast enhancement.

Dosage form: all approved dosage forms of an active ingredient must be offered

Concentrations: must be offered cumulatively

1. 300 mg / ml - 320 mg / ml,

2. 350 mg / ml - 400 mg / ml (all concentrations of an active ingredient must be offered, at least all areas of application must be covered).

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 of the request for offer.

Description: Non-ionic iodine-containing monomeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intrathecal. More possible

Application areas:

- cervical, thoracic and lumbar myelography and radiculography,

- CT myelography.

Dosage form: all approved dosage forms of an active ingredient must be offered.

Concentration:

200 mg / ml - 300 mg / ml (all concentrations of an active ingredient must be offered)

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 to the request for quotation.

Description: Non-ionic iodine-containing monomeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous and intracavity. More possible

Application areas:

- urography,

- venography,

- CT contrast enhancement,

- Digital subtraction angiography

Dosage form: all approved dosage forms of an active ingredient must be offered.

Concentration: 150 mg / ml-250 mg / ml, all concentrations of an active ingredient must be offered.

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 to the request for quotation.

Description: Non-ionic iodine-containing dimeric, low-osmolar, water-soluble nephrotropic X-ray contrast media

Application: intra-arterial and intravenous. More possible

Application areas:

- Cerebral angiography, abdominal angiography, peripheral arteriography, venography

- urography,

- Contrast enhancement in computed tomography (CT).

Concentrations: must be offered cumulatively:

1.270 mg / ml

2. 320 mg / ml.

(all concentrations of an active ingredient must be offered, at least all areas of application must be covered)

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular linear contrast media for MRI

Application: Intra-articular application

Application areas:

- direct magnetic resonance arthrography.

NSF risk: high NSF risk class

Dosage form: all dosage forms of the active ingredient for this indication

Concentration: 0.002 mmol / ml

Pack size: all pack sizes of the active ingredient for this indication

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular macrocyclic contrast media for MRI

Application: intravenous. More possible

NSF risk: low NSF risk

Application areas:

- Cranial and spinal magnetic resonance tomography,

- MRI of other organs.

Dosage form: all approved dosage forms of an active ingredient must be offered.

Concentration: all concentrations of an active ingredient must be offered.

Pack size: all approved pack sizes of an active substance must be offered.

Further information can be found in Appendix 11 to the request for quotation.

Name: Paramagnetic extracellular macrocyclic contrast media for MRI

Application: Intra-articular application

Applications: direct magnetic resonance arthrography

NSF risk: low NSF risk class

Dosage form: all dosage forms of the active ingredient for this indication

Concentration: 0.0025 mmol / ml

Pack size: all pack sizes of the active ingredient for this indication

Further information can be found in Appendix 11 to the request for quotation.