The Unit for Molecular Pathology will procure a sequencing platform (NGS) that can be used for mutation analyses of DNA and RNA for haematological neoplasia and solid growths, lung cancer, colorectal cancer, melanoma, sarcoma and other types of growth. The platforms must be suitable for the detection of SNV, splicing, copy number changes and RNA fusion transcripts. In the future the system will also be used for mutation analyses of cfDNA in plasma and MRD analyses.

An equipment package will be needed, including minimum 2 different sequencers to cover the need.

There must be instrumentation for analysis panels that carry out minor sample amounts several times a week and major sample amounts 1-2 times a month.

In addition instrumentation is needed for emergency help analyses for selected panels. Different types of NGS instruments are therefore deemed to be necessary in order to meet the current need, as well as new future needs.

Tenders are therefore wanted for an equipment package that gives flexibility as regards the amount of samples per run, frequency, panel size, depth and reading amount.