The State Office for Nature, Environment and Consumer Protection of the State of North Rhine-Westphalia (LANUV NRW) intends to purchase several laboratory equipment of different types, which are to be procured for various branch offices of the Office.

LANUV NRW intends to procure a TD-GC-MS system for the determination of volatile organic compounds (VOCs) as ozone precursors in outdoor air. It must be possible to analyse different classes of non-polar and polar VOCs from the revision of the EU Ambient Air Quality Directive (see the range of substances in the annex under "Section 2-Measurements of ozone precursor substances") after sampling on TD tubes, from canisters and also online with appropriate water management.

Only a new device is to be offered.

General requirement:

Analysis system for VOCs using gas chromatography and detection via flame ionization detector (FID) and mass spectrometer (MSD) with pre-concentration and focusing on cooled trap and subsequent thermal desorption

Sample feeding via thermal desorption unit, which is suitable for sampling on packed tubes (dimensions ØxL 6x89 mm or 1/4x3.5"), as well as from canisters or completely online directly from the outside air

(Cooling) trap with inlet and outlet split including recovery/recapture of the split eluate on freshly conditioned TD tube

Different flow direction during adsorption and desorption of the trap for combination sorbents

Chromatographic separation of VOCs from a sample in parallel at two different stationary phases (e.g. separation at polar SP after pre-separation on non-polar SP, heartcutting) by pneumatic switching (Deans Switch)

A separate detector for each separation column, parallel FID and MS detection

Possibility of sampling, separating and analyzing different classes of VOCs, explicitly including oxygenated VOCs even with canister or online sampling (alcohols min. C2, aldehydes min. C1-C4, alkynes min. C2, alkanes min. C2-C8, alkenes min. C2-C6, aromatic hydrocarbons min. BTEX + trimethylbenzenes, ketones min. C3-C4, terpenes min. isoprene + a-, mono- and bicyclic monoterpenes (see also appendix chapter "Section 2-Measurements of ozone precursor substances"). Proof must be provided in the form of published applications or articles in specialist journals.

Water removal unit for the simultaneous analysis of ultra-VOCs and polar VOCs (see list of substances above) without quantitative loss in canister and online samples. Proof must be provided in the form of published applications or articles in specialist journals.

Tube, canister and online samples can be measured within a sequence

Electronic and thus liquid nitrogen-free cooling of the trap to enable use as a measuring station in the field (at least coolable to -30 °C)

High measurement stability (RSD>10%), at low detection and determination limits (

Certification of the TD and GC-MS system for hydrogen as a carrier gas. Compatibility with hydrogen, nitrogen and helium.

It must be demonstrated that when hydrogen is used as a carrier gas under standard conditions for EI ionization, surface-catalyzed reduction reactions are reduced to a minimum in order not to obtain significantly different mass spectra than under helium as a carrier gas (for NIST database comparison)

Automatic sample change of tubes and canister samples possible (multi-/autosampler or multi-port valve)

Capacity for at least 10 canisters and 90 tubes in one system

The caps for storing the tubes in the autosampler remain on the tubes during automated desorption

Option to inject liquid samples for calibration/identification from liquid standards

Option to connect test gas cylinders for calibration from gaseous standards

Integrated pressure sensors to check the impedance and tightness of the system

Predominantly electronic flow/pressure controls

GC furnace exhaust air discharged upwards as far as possible

Software:

The software must run stably under Windows 10 or higher and be network-compatible

Complete software(s) needed to control TD and GC-MS systems

All operations and device parameters required for operation must be controlled and monitored by the software(s).

The software must allow simultaneous data acquisition and data evaluation

The control software must have a logbook that can be used to track error messages or device status after unattended operation

Automatic diagnostic options for TD-GC-MS system

Permanent verification of the tightness of the system

In the evaluation software, it must be possible to subsequently adjust the integration of the peaks in the chromatograms and create tables for automatic integration

It must be possible to export chromatograms as graphic files of common formats

Export of analysis results to a LIMS (e.g.CSV)

Creation of an analysis sequence for multiple samples, which is automatically controlled unattended, e.g. overnight

Automatic and manually customizable creation of reports

Comparison of mass spectra with NIST database integrated into evaluation software

Remote access, e.g. via browser interface, to devices with the following functionalities:

Check instrument status and perform diagnostics from anywhere within the network, regardless of the PC you are using

Multiple simultaneous access to the status of the instrument from any location within the network

Guided maintenance work with control of the GC to automatically cool heating zones such as the inlet system when changing the liner

The GC should be able to carry out the following self-diagnostic tests for the inlet system directly at the user interface as well as remotely fully automatically, e.g. via a browser interface, without having to intervene manually on site, such as blocking the split line

Leak and restriction test

Split valve restriction test

Pressure drop test

......

In addition, reference is made to the document Specifications Lot 1

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW

intends to procure a GC-MS-MS system with a split/splitless injector, multifunctional sample feeding system including sample preparation options, mass-selective detector incl. MS-MS function (triple-quad) for the examination of environmental samples for organic trace substances, in particular for organophosphorus compounds, in water and solid samples

Geräteanforderungen

The GC-MS-MS system must include the following modules/components with the above requirements:

Generally:

It must be possible to control the operation of the gas chromatograph, the injector, the autosampler and the MS-MS detector from one software. Electronic control of the necessary gas flows (e.g. split/septum/column, etc.) is required, as well as control of constant flow or constant pressure. It is imperative that the complete control software for all modules can be operated from a software interface with only one sequence table.

1. Gaschromatograph - Injektionssystem

- Oven temperature controllable from ambient temperature + 4 °C to 450 °C

- Oven programmable with at least 20 temperature ramps/plateaus

- Sufficiently large furnace chamber for 2 columns with heating shutdown when the door is opened

- Automatic shutdown in the event of a significant drop in the inlet pressure

- the possibility of using helium or hydrogen as a carrier gas on an optional basis; Hydrogen sensors, automatic shutdown of the gas supply in case of H2 leaks are required

- Repeatability of retention times < 0.008 % and peak areas of < 1 % RSD

- PTV injector with septum feed head

- Quick liner change; The possibility of automation must be given

- Injector temperature can be adjusted to 10 °C at a maximum furnace temperature of 70 °C, e.g. with Peltier cooling. No cooling by means of liquid nitrogen, dry ice, synthetic air or nitrogen.

- Rückspülbare Vorsäule (Backflush-System)

- 2 capillary columns DB5-ms UI, length 25 m, ID 0.25 mm, film thickness 0.25 μm

- Exhaust air outlets (oven, split) must be able to be connected to the exhaust air

- the possibility of using helium or hydrogen as a carrier gas on an optional basis; Hydrogen sensors, automatic shutdown in case of H2 leaks are required.

2. Mass Selective Detector (MS-MS)

- EI mode - 10 to 300 eV selectable

- SIM, scan and synchronous SIM/scan data acquisition from one injection

- Mass range up to 1000 (m/z)

- Mass axis stability < +/- 0.1 u over 24 hours

- MRM speed: 800 transitions/s

- Triple quad detector with MS-MS function

- Double filament (EI) - switching in case of failure of a filament

- Automatable SRM (selected reaction monitoring) for productions, precursor ions and collision energies for method development

- Integrated self-cleaning function of the ion source

- Turbopumpenbetrieb mind. 250 l/s (He) inkl. Vakuummessgerät

- Backing pump: no scroll pump

- Detection of sensitivity during installation: 0.5 fg octafluoronaphthalene (instrumental detection limit)

- Signal-to-noise ratio: > 600:1 with a 1 μL injection of 2 fg/μL OFN in MS-MS mode for transition 272 -> 222

- Exhaust air outlets (MSD) must be able to be connected to the exhaust air

3. Autosampler for the gas chromatograph

Type: xyz robot suitable for all injector stations (TriPlus RSH Autosampler, Combi-PAL or comparable) with the functions for:

- the feeding of extracts incl. coolable sample plate for approx. 80 sample vessels (2 ml each)

- Automated sample preparation in modular design:

for the preparation of dilutions from defined extracts

for the addition of solutions into defined extracts

- Tray holder for 2 mL vials

- 3 syringe modules for 10 μL, 50 μL and 1 mL syringes including double syringe set

- Standard washing module for 4 x 10 mL solvent vials and 1 x 10 mL waste vial

- High Flow Fast washing module for 2 x 1 L solvent bottles with a drop position

- Solvent module for 3 x 180 mL solvent bottles, e.g. for reagent solutions

- 5 L waste bins for solvents

- Shaking unit for 2 mL vials

- the complete integration of the control software for the autosampler into the control software of the GC-MS-MS system via a single sequence list

- Width of the autosampler: 120 cm +/- 10 cm

3. Control and evaluation unit

- Computer with current Windows 11 operating system to control the GC, MSD and autosampler as well as necessary Windows programs (Word, Excel)

- Compatibility with existing evaluation software must be given.

Existing software MassHunter:

Data intake: 10.0 - Quantification: 10.2 - Qualitative analysis: 10.0

- Evaluation unit for processing chromatograms and data

- Evaluation data can be copied to Excel

- Automatic determination of transitions as well as automatic optimization of collision energies via the software

- Common mass spectra library (NIST) in the current version

- min. 24 inch TFT monitor

4. Connection to in-house network

The computer of the GC-MS-MS system must be able to be connected to the house network so that remote connections can be controlled from other computers. Special structural measures do not have to be carried out.

5. Others

- All operating instructions on data carriers or in the form of manuals in English or German

- All software products on data carriers

- On-site installation with instruction for 4 people

- Extended instruction on how to use the system including method development according to the user's specifications (2 days)

2 year warranty

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW

intends to procure a GC-MS-MS system with a split/splitless injector, multifunctional sample feeding system, mass-selective detector incl. MS-MS function (triple-quad) for the examination of environmental samples for organic trace substances, in particular chlorinated paraffins and nitrogen-phosphorus compounds, in water and solids samples, as well as for screening investigations. Application of the EI or CI technique.

Geräteanforderungen

The GC-MS-MS system must include the following modules/components with the above requirements:

Generally:

It must be possible to control the operation of the gas chromatograph, the injector, the autosampler and the MS-MS detector from one software. Electronic control of the necessary gas flows (e.g. split/septum/column, etc.) is required, as well as control of constant flow or constant pressure. It is imperative that the complete control software for all modules can be operated from a software interface with only one sequence table.

1. Gaschromatograph - Injektionssystem

- Oven temperature controllable from ambient temperature + 4 °C to 450 °C

- Oven programmable with at least 20 temperature ramps/plateaus

- Sufficiently large furnace chamber for 2 columns with heating shutdown when the door is opened

- Automatic shutdown in the event of a significant drop in the inlet pressure

- the possibility of using helium or hydrogen as a carrier gas on an optional basis; Hydrogen sensors, automatic shutdown of the gas supply in case of H2 leaks are required

- Repeatability of retention times < 0.008 % and peak areas of < 1 % RSD

- PTV injector with septum feed head

- Quick liner change; The possibility of automation must be given

- Injector temperature can be adjusted to 10 °C at a maximum furnace temperature of 70 °C, e.g. with Peltier cooling. No cooling by means of liquid nitrogen, dry ice, synthetic air or nitrogen.

- Rückspülbare Vorsäule (Backflush-System)

- 2 capillary columns DB5-ms UI, length 25 m, ID 0.25 mm, film thickness 0.25 μm

- Exhaust air outlets (oven, split) must be able to be connected to the exhaust air

- the possibility of using helium or hydrogen as a carrier gas on an optional basis; Hydrogen sensors, automatic shutdown in case of H2 leaks are required.

?

2. Mass Selective Detector (MS-MS)

- EI mode - 10 to 300 eV selectable

- CI mode incl. CI ionization unit (positive and negative CI)

- SIM, scan and synchronous SIM/scan data acquisition from one injection

- Mass range up to 1000 (m/z)

- Mass axis stability < +/- 0.1 u over 24 hours

- MRM speed: 800 transitions/s

- Triple quad detector with MS-MS function

- Double filament (EI) - switching in case of failure of a filament

- Automatable SRM (selected reaction monitoring) for productions, precursor ions and collision energies for method development

- Integrated self-cleaning function of the ion source

- Turbopumpenbetrieb mind. 250 l/s (He) inkl. Vakuummessgerät

- Backing pump: no scroll pump

- Detection of sensitivity during installation: 0.5 fg octafluoronaphthalene (instrumental detection limit)

- Signal-to-noise ratio: > 600:1 with a 1 μL injection of 2 fg/μL OFN in MS-MS mode for transition 272 -> 222

- Exhaust air outlets (MSD) must be able to be connected to the exhaust air

3. Autosampler for the gas chromatograph

Type: xyz robot suitable for all injector stations (TriPlus RSH Autosampler, Combi-PAL or comparable) with the functions for:

- the feeding of extracts incl. coolable sample plate for approx. 80 sample vessels (2 ml each)

- Possibility of extension to other sample application techniques (e.g. derivatization, dynamic headspace, sample preparation by means of solid phase extraction)

- the complete integration of the control software for the autosampler into the control software of the GC-MS-MS system via a single sequence list

- Width of the autosampler: 120 cm +/- 10 cm

3. Control and evaluation unit

- Computer with current Windows 11 operating system to control the GC, MSD and autosampler as well as necessary Windows programs (Word, Excel)

- Compatibility with existing evaluation software must be given.

Existing software MassHunter:

Data intake: 10.0 - Quantification: 10.2 - Qualitative analysis: 10.0

- Evaluation unit for processing chromatograms and data

- Evaluation data can be copied to Excel

- Automatic determination of transitions as well as automatic optimization of collision energies via the software

- Common mass spectra library (NIST) in the current version

- min. 24 inch TFT monitor

4. Connection to in-house network

The computer of the GC-MS-MS system must be able to be connected to the house network so that remote connections can be controlled from other computers. Special structural measures do not have to be carried out.

5. Others

- All operating instructions on data carriers or in the form of manuals in English or German

- All software products on data carriers

- On-site installation with instruction for 4 people

- Extended instruction on how to use the system including method development according to the user's specifications (2 days)

2 year warranty

Delivery of free place of use including transport, installation, commissioning and installation testing to the

The place of delivery must be observed in section 12.3 of the tender regulations!

The contractor shall coordinate the handover date with the client at least two weeks in advance. The contractor will be given the contact person when the order is placed. If a delivery cannot be made on the agreed date, the contractor is expressly prohibited from arbitrarily setting an alternative date. An alternative date must be agreed with the client.

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure an ICP-MS system. As part of the monitoring of surface waters according to WFD and groundwaters, metals such as cadmium, lead, arsenic, etc. must be analysed in low concentrations.

Geräteanforderungen:

The ICP-MS system must include the following modules/components with the specified requirements:

Conformity to standards: Fulfillment of the requirements according to DIN EN ISO 17294-2 (01/17) "Water quality, application of inductively coupled plasma mass spectrometry (ICP-MS) Part 2: Determination of selected elements including uranium isotopes"

Basic unit as a table-top device (sample feeder, flare, quadrupole, detector, vacuum pump, cooling unit, mass flow controller for all gases)

Sample feeding system (incl. torch and injector) with low-pulsation, peristaltic pump with at least 3 channels, atomizer chamber and fast system (see also "Autosampler"). No rubber seals in the entire sample feeding system

Plasma: Robust, maintenance-free, long-lasting 27 MHz RF generator. Easy to adjust torch with automatic positioning. The positioning must be done together with the induction coil for optimal alignment. Programmable ignition and shutdown of the plasma

Vacuum system consisting of an external rotary pump and a turbomolecular pump.

Minimized noise pollution due to the highest possible sound insulation:

Sound cover for vacuum pump. This must fit under the table (90 cm (W)x80 cm (D)x90 cm (H)). The pump heat must be dissipated by active ventilation

It must be possible to change cones without interrupting the high vacuum. Separation of neutral particles by ion lenses and photon stop even before the high vacuum system (slide valve). A deflection of the ion beam by 90 degrees is not desired in order to obtain the highest possible sensitivity in the lower mass range

Closed collision cell (multipole) with a collision gas connection for helium in the high vacuum range.Targeted dissociation of argon-based disturbances exclusively with helium (e.g. on selenium)

Combined reaction and collision cell for operation with helium/hydrogen mixture or other reaction gases

Switching and stabilization time between the different measurement modes, e.g. between helium mode and standard mode, less than five seconds, demonstrably proven

Mass spectrometer:

Quadrupole mass range from 2 to 260 amu. Mass resolution 0.3 to 1 AMU Odd doubly charged ions do not interfere on half the mass +/- 1/2 (e.g. 149Sm++ and 151Eu++ do not interfere on ground 75As and the mass 74.5 can be used to correct 75 with respect to Sm++ perturbation.)

Detector: orthogonal detector system with special low background due to 90 degree off-axis arrangement dual-mode with 10 orders of magnitude dynamic range (0.1 to 4 Gcps)

Ceroxidrate (CeO/Ce) ? 1,5 % im No-Gas-Standard-Modus

The limits of quantification given in the Annex (calculated as 9 times the standard deviation of the blank value method) in an artificial water matrix (100 mg/l Ca and 100 mg/l Cl) are at least achievable at a cerium oxide rate (CeO/Ce) ? 1.5 % and can be proven by means of measurement data (raw data, associated performance check) including calculation

Resistance to acids and acid mixtures (nitric acid, hydrochloric acid and aqua regia)

Ready for operation up to at least 30°C room temperature

Abluftvolumen 420 m3/h

Circulating cooling to provide the cooling water: water/water cooler from van der Heijden for connection to the process cooling water in the laboratory. Connection is made by the customer service of the device manufacturer of the ICP-MS. A quiet and low-vibration model must be selected

autosampler

For at least 94 positions when using 50ml autosampler tubes, distributed as follows: At least 10 fixed positions for 50ml sample vessels for standard solutions and 4 positions for sample tubes (at least 4x21x 50 ml. sample vessels)

Full number of racks

Easy and stable positioning of the racks on stable floors made of non-deformable material

Matching dust cover with connection to the exhaust air device

Fastsystem (sample feeding system by means of a sample loop) for fast, precise and stable sample feeding through fully integrated switching valve (in hardware and software) from the ICP-MS manufacturer (not a third-party company)

The complete integration of the control software for the autosampler and the sample feeding system system into the control software of the ICP-MS

Editability of running sequences, so that additions are possible during measurement operation

Connected scanner for reading barcodes and QR code for filling the sample tables

The control or evaluation computer is based at least on Windows 11 in the latest version for controlling the ICP-MS and the autosampler with external hard drive for data backup. If the operating system is not in the latest version, the upgrade must be carried out free of charge within 2 years after acceptance of the entire software range supplied, subject to availability. If the delivered measuring computer does not meet the minimum requirements for Windows 11, it must also be replaced free of charge

Comprehensive system software with summary overview of the measurement results as an MS Excel compatible file

Indication of units in (derived) SI units (example: not ppb but μg/l, not ppm but mg/kg)

In the software, it must be possible to specify the weight and the dilution volume for solid extracts (e.g. aqua regia extract) so that the result can be displayed in a solid/solid unit

System parameter documentation according to DIN EN ISO 17025

Current Windows Office package

two 24" TFT monitors

Laser printer b/w

At least 3 offline licenses for software use on other computers, e.g. to be able to make evaluations

For further details, see document Service Description Lot 12

The State Office for Nature, Environment and Consumer Protection of North Rhine-Westphalia intends to procure a live cell analysis system for cell cultures.

Only a new device is to be offered.

A detailed description of the devices must be attached to the offer in electronic form (CD-ROM or USB stick) in German and English. If a German description is not available, the claim is limited to the English version.

After the contract has been awarded and the order has been placed, detailed operating instructions in German and English in the form of manuals and in electronic form (e.g. CD-ROM or USB stick) must be supplied with the devices. If there are no detailed German versions, the claim is limited to the delivery of the English version.

The following requirements are minimum requirements

conditions

General requirements

Live cell analysis system with a total of up to 5 different fluorescence channels, for the analysis of adherent and non-adherent cells over longer periods of time (days and several weeks)

Independent planning of experiments

Equipped with an NIR fluorescence channel for cell-gentle multiplexing with 3 colors simultaneously

It must be possible to change the fluorescence channels within the experiments

CE marking according to the EMC Directive and the Low Voltage Directive

Technical Requirements

Fully automatic lens change within the self-defined experiments between 4x, 10x and 20x magnification

Automated image acquisition including autofocusing and autolocalization (optical unit movable, cells remain at rest to exclude interference from additional movements)

6 assay slots for microtiter plates (6-384Well) from any manufacturer

6 assay slots for T-bottles (75 cm2) from any manufacturer

Optionally possible: Slots for Petri dishes and slides can be retrofitted

Software for label-free cell counting and analysis of subpopulations

Software to count live/dead cells or classify cells based on their morphology through label-free multivariate analysis

Software to segment cells and classify them as alive or dead to assess cell health without fluorescent labels

Immediate storage capacity of the system at least 20 TB

Equipped with CMOS camera

Ability to expand memory on demand

Uninterruptible power supply (230 V)

In combination with an H2O2 sterilizable incubator, the system must be able to be decontaminated in the same step as the H2O2 incubator without damaging the device

Maximum dimensions 50 cm x 50 cm (width, depth)

Maximum weight 25 kg

Usability and user-friendliness

Free user licenses (any number) for the operating and analysis software

Connection of the system and the database of the system to an internal network (Intra-net) for the joint use of the system for simultaneous analysis and evaluation of data sets

Synchronous planning and execution of experiments locally and remotely

Warranty and customer service

Customer service for the device system in Germany must be available

at least 12 months warranty

At least 10 years of spare parts availability guaranteed

Installation, delivery and installation location

Delivery free of charge to the place of use including transport, installation, commissioning and installation testing to the

The place of delivery must be observed in section 12.3 of the tender regulations!

The contractor shall coordinate the handover date with the client at least two weeks in advance. The contractor will be given the contact person when the order is placed. If a delivery cannot be made on the agreed date, the contractor is expressly prohibited from arbitrarily setting an alternative date. An alternative date must be agreed with the client.

After successful completion of the installation test and the instruction of the employees, the functional test is also completed and acceptance by the client is declared. From this point on, the warranty period / warranty period begins. Partial acceptances are not declared.

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure a GC system with a non-discriminatory, temperature-programmable injector, multifunctional autosampler and mass-selective detector including MS-MS function (Triple Quad - Tandem Quadrupole Mass Spectrometer) for the examination of environmental samples for organic trace substances

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure a mass spectrometer for the examination of samples for organic trace substances in water for timely water monitoring.

Geräteanforderungen

The mass spectrometer (MS) is to be integrated into a system consisting of the following components as a replacement for an older MS (Varian, now Agilent):

Gerstel MPS2 autosampler (ser. no. 127473),

Gerstel cold feed system KAS4 with UPCplus (serial number of the controller: 07410-02547),

Agilent 7890B Gas Chromatograph (Ser.-No. CN13403024 with GCHI on the right).

For the operation of the entire system, a personal computer and software for controlling the equipment, recording and evaluating the chromatograms (hereinafter referred to as a workstation) must be supplied.

1. Quadrupole mass spectrometer

- Turbopumpenbetrieb mind. 240 l/s (He)

- Ölfreie Vorvakuumpumpe

- Graphpack adapter for the GC/MS transferline

- EI ion source (70 eV) with double filament

- heated quadrupole

- Single mass resolution in full scan in the range from m/z 10 to 650 with a scan rate of min. 5 Hz

- SIM mode preferably quasi-parallel with fullscan in an experiment

2. Computer

- The recording of chromatograms must be fully controllable from a workstation with a Windows operating system - even under remote access to the computer in question. This is especially true for starting and stopping sequences.

- German keyboard, mouse, DVD, 24" monitor with 1920x1200 resolution

- Intel Core i7 (or better), min. 32 GB RAM, 500 GB SSD, 2x LAN, 6x USB

- free 2TB HDD NOT in RAID configuration,

- 3-4x RS232,

- Windows 10 prof., Office 2021

- For integration into the instrument network, the computer must provide a free Ethernet connection for connected devices

- At least one slot must be left free in the computer for a PCI card.

3. Instruments-Software (Workstation)

- The software must be able to programmatically execute series of analyses (sequences), whereby a special procedure (method) can be specified for each experiment. Alternatively, the system must be able to process several sequences one after the other using different methods.

- Tables with the analyses to be executed must be able to be imported from text files.

- The control of GC and MS must be stored in a single method file.

- The evaluation software must include automatic and manual peak detection, calibration and quantification taking into account internal standards, library search for mass spectra and an editor for creating libraries.

- Tables with analysis reports must be automatically generated and stored in text files or Excel files.

- The software must be able to export mass spectra to the NIST program for spectral comparison. In addition, you must be able to open the raw data files with AMDIS.

- An upgrade of the NIST library to the current version must be included.

- The documentation must contain an exact description of the format of the raw data, so that scans with retention times, mass numbers, intensities can be read by programmers.

Alternatively, a program must be supplied that stores the corresponding information completely in text files - preferably automatically as a post-run after each analysis.

- It must be possible to disable restrictions on the execution of the software for certain users.

- It must be possible to switch off all GLP functions.

4. Miscellaneous

- The PC must be integrated into the laboratory network before installing the instrument.

- The installation of the workstation software must be demonstrated on site and documented in cooperation with the laboratory staff. This takes about half a day.

- Instruction in the use of tuning, method editor, starting and stopping sequences, evaluation, etc. on three days on site for three people

- Optional external training for other people

5. Warranty

- Warranty is at least 24 months

All operating instructions and device manuals on data carriers or in the form of manuals in English, preferably in German.

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure a GC-FID system with a PTV injector, multifunctional autosampler for liquid injection for the examination of environmental samples for KW index.

The GC-FID system must contain the following modules/components:

1 GC and RCD detector from one manufacturer

Operation of the GC device with hydrogen

The operation of the gas chromatograph, the injectors, the autosampler and the RCD detector must be controlled by software. Electronic control of the necessary gas flows (e.g. split/septum/column, etc.) is required, as well as control of constant flow or constant pressure. All exhaust air outlets (furnace, split, FID) must be able to be connected to an exhaust system.

Complete control software for all modules must be able to be operated from one interface with only one sequence table.

2 Gaschromatograph

Exhaust air outlets (furnace, split, FID) must be able to be connected to the exhaust air

Oven temperature controllable from ambient temperature + 4 °C to 450 °C

Oven programmable with at least 20 temperature ramps

Sufficiently large furnace chamber for 2 columns with heating shutdown when the door is opened

Automatic shutdown in the event of a significant drop in the inlet pressure

Wasserstoffsensor

Repeatability of retention times < 0.008 % and peak areas of < 1 % RSD

Column: DB5, 30 m x 0.32 mm x 0.25 μm

3 Aufgabesystem

PTV injector for liquid injection

septum-free feeding head at PTV (Merlin feeding system is not sufficient)

PTV temperature programmable from 10 °C to 450 °C

Injection (also large-volume injection) by autosampler

Split can be adjusted without changing the column flow

Direct heating control - non-ballistic (freely selectable temperature program with 2 temperature ramps)

Heizrate 12°C/sec (16°C/sec bis 150°C)

Injector cooling without the use of gases (air / CO2) or liquid nitrogen for spatial and occupational safety reasons

Large-volume injection as a software preset

4 Flame ionization detector

minimum detection level (for tridecane) < 1.2 pg C/s

linear dynamic range > 107

Data rate of up to 1000 Hz for very narrow peaks up to a width of 5 ms at half height

max. operating temperature 450 °C

5 autosamplers for liquid injection in GC

Also suitable for the use of 2 injectors in the GC when retrofitting the 2nd channel. Type xyz robot

Feeding of samples incl. sample tray for approx. 160 sample vessels (2 ml each)

Full integration of the control software for the autosampler into the control software of the GC-MS-MS system

An extension to other sample application techniques (headspace, pyrolysis, dynamic headspace to increase sensitivity, derivatization, overhead shakers for automated liquid-liquid extraction, sample preparation by means of solid phase extraction) must be possible modularly

It must be possible to edit running sequences and insert "urgent samples" at any time, even during operation

It must be possible to control two injectors

Parking station for syringe holders on the device

6 Control and evaluation unit - demand position -

Computer with current Windows operating system (at least WINDOWS 10) for controlling the GC-FID system

Mind. 24 Zoll TFT-Monitor

Software for control and evaluation must be compatible with the existing systems (Agilent Technologies - Open Lab Software); Same data format for flexible evaluation options

Control of the entire system (all modules including feeding system and autosampler) via only one method and one sequence list

Editing of running sequences must be possible

Control software of the current GC settings in real time, as well as fault diagnosis

Complete systems can be controlled via an Ethernet network

Current MS-Office in English

7 Gerätehandbuch

Versions of the manuals, as far as possible, in German and electronic form

Manual of the gas chromatograph with operating instructions and application examples

Manual of the PTV injector with operating instructions and application examples

FID manual with operating instructions and application examples

Manual of the autosampler with operating instructions as well as application examples for the injection of liquids

Manual and demonstrations on how to use the software

8 Installation

The system must be designed in such a way that the control PC can stand up to 15 m away from the device

It must be possible to connect the control PC via a network to another PC in another room for device operation and evaluation via remote access.

All software products on data carriers.

9 Briefing

Anwendertraining

User training for up to 5 people (approx. 2 days) for on-site training and handling of the device (in our own laboratory) The user training takes place directly after the installation and instruction of the devices by arrangement

10 Miscellaneous

The warranty period for the complete hardware is at least two years

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure a GC-MS system with a PTV injector, multifunctional autosampler for headspace and liquid injection for the examination of environmental samples for LHCs and BTX

1 GC and MS detector from a manufacturer with the highest sensitivity level

Operation of the GC and MS device with helium and hydrogen

The operation of the gas chromatograph, the injectors, the autosampler and the MS detector must be controlled from one software. Electronic control of the necessary gas flows (e.g. split/septum/column, etc.) is required, as well as control of constant flow or constant pressure. All exhaust air outlets (furnace, split, MSD) must be able to be connected to an exhaust system.

Complete control software for all modules must be able to be operated from one interface with only one sequence table.

2 Gaschromatograph

Exhaust air outlets (furnace, split, MSD) must be able to be connected to the exhaust air

Oven temperature controllable from ambient temperature + 4 °C to 450 °C

Oven programmable with at least 20 temperature ramps

Sufficiently large furnace chamber for 2 sows with heating shutdown when the door is opened

Automatic shutdown in the event of a significant drop in the inlet pressure

Possibility of optional use of helium or hydrogen as a carrier gas

Repeatability of retention times < 0.008 % and peak areas of < 1 % RSD

Column: HP5 MS, 60 m x 0.25 mm x 0.25 μm

Possibility to retrofit the backflush as pre-colunm / mid-colunm / post-colunm

3 Aufgabesystem

PTV injector for liquid and headspace injection

septum-free feeding head at PTV (Merlin feeding system is not sufficient)

PTV temperature programmable from 10 °C to 450 °C

Injection (also large-volume injection) by autosampler (see pos. 5)

Split can be adjusted without changing the column flow

Direct heating control - non-ballistic (freely selectable temperature program with 2 temperature ramps)

Heizrate 12°C/sec (16°C/sec bis 150°C)

Injector cooling without the use of gases (air / CO2) or liquid nitrogen for spatial and occupational safety reasons)

Large-volume injection as a software preset

4 Mass selective detector

with the highest sensitivity level of the product range

NON-Modus

Mass range from 0.6 to at least 1090 m/z

Actively heated quadrupole up to 200°C

Proof of sensitivity when installing: 1.5 fg IDL

(IDL statistically derived at 99 % confidence level from the area precision of eight sequential splitless injections of OFN (octafluoronaphthalene)

IDL measured using 10 fg injection, 1 ? L injection

Signal/noise sensitivity: 2000:1 at a 1ul injection of 0.1 pg/ul OFN

Mass axis stability: < 0.10u over 48 hours

Massengenauigkeit +/- 0,005a

Scan rate: up to 20,000 rpm

Turbopump operation, incl. vacuum gauge, with software-controlled automatic rapid ventilation as well as corresponding calculations and display via the software

Dynamic Range 10E6

2 filaments for switching in case of defect of the active filament

Oil-free diaphragm backing pump (no scroll pump)

NIST Database

vacuum gauge

5 autosamplers for headspace injection in the GC.

Also suitable for the use of 2 injectors in the GC when retrofitting the 2nd channel. Type xyz robot

Feeding of samples incl. sample tray for at least 60 headspace samples in 20 ml tubes

Full integration of the control software for the autosampler into the control software of the GC-MS-MS system

It must be possible to expand to other sample application techniques (dynamic headspace to increase sensitivity, pyrolysis, derivatization, overhead shakers for automated liquid-liquid extraction, sample preparation by means of solid phase extraction) in a modular manner

It must be possible to edit running sequences and insert "urgent samples" at any time, even during operation

It must be possible to control two injectors

Parking station for syringe holders on the device

6 Control and evaluation unit - demand option -

Computer with current Windows operating system (at least Windows 10) for controlling the GC-MS overall system

Mind. 24 Zoll TFT-Monitor

Additional evaluation license of the software for use on a PC

Software for control and evaluation must be compatible with the existing systems (Agilent Technologies - Masshunter Software); Same data format for flexible evaluation options

Control of the entire system (all modules including feeding system and autosampler) via only one method and one sequence list

Editing of running sequences must be possible

Control software of the current GC settings in real time, as well as fault diagnosis

Complete systems can be controlled via an Ethernet network

Current MS-Office in English

NIST database in the current version

7 Gerätehandbuch

Versions of the manuals, as far as possible, in German and electronic form

Manual of the gas chromatograph with operating instructions and application examples

Manual of the PTV injector with operating instructions and application examples

Manual of the MS-MS device with operating instructions and application examples

Manual of the autosampler with operating instructions as well as application examples for the injection of liquids

Manual and demonstrations on how to use the software

8 Installation

The system must be designed in such a way that the control PC can stand up to 15 m away from the device

It must be possible to connect the control PC via a network to another PC in another room for device operation and evaluation via remote access.

All software products on data carriers.

9 Briefing

User training for up to 5 people (approx. 2 days) for on-site training and handling of the device (in our own laboratory) The user training takes place directly after the installation and instruction of the devices by arrangement

Training of the software for 1st person at the manufacturer

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure a GC-MS system with a PTV injector, multifunctional autosampler for liquid injection for the examination of environmental samples for PCBs in solids and liquid waste

1 GC and MS detector from one manufacturer

Operation of the GC and MS device with helium and hydrogen

The operation of the gas chromatograph, the injectors, the autosampler and the MS detector must be controlled from one software. Electronic control of the necessary gas flows (e.g. split/septum/column, etc.) is required, as well as control of constant flow or constant pressure. All exhaust air outlets (furnace, split, MSD) must be able to be connected to an exhaust system.

Complete control software for all modules must be able to be operated from one interface with only one sequence table.

2 Gaschromatograph

Exhaust air outlets (furnace, split, MSD) must be able to be connected to the exhaust air

Oven temperature controllable from ambient temperature + 4 °C to 450 °C

Oven programmable with at least 20 temperature ramps

Sufficiently large furnace chamber for 2 sows with heating shutdown when the door is opened

Automatic shutdown in the event of a significant drop in the inlet pressure

Possibility of alternating use of helium or hydrogen as a carrier gas

Repeatability of retention times < 0.008 % and peak areas of < 1 % RSD

Column: HP5 MS, 30 m x 0.25 mm x 0.25 μm

Possibility to retrofit the backflush as pre-colunm / mid-colunm / post-colunm

3 Aufgabesystem

PTV injector for liquid injection

septum-free feeding head at PTV (Merlin feeding system is not sufficient)

PTV temperature programmable from 10 °C to 450 °C

Injection (also large-volume injection) by autosampler

Split can be adjusted without changing the column flow

Direct heating control - non-ballistic (freely selectable temperature program with 2 temperature ramps)

Heizrate 12°C/sec (16°C/sec bis 150°C)

Injector cooling without the use of gases (air / CO2) or liquid nitrogen for spatial and occupational safety reasons)

Large-volume injection as a software preset

4 Mass selective detector with sensitive extraction ion source

NON-Modus

Mass range from 0.6 to at least 1090 m/z

Actively heated quadrupole up to 200°C

Proof of sensitivity when installing: 10 fg IDL

(IDL statistically derived at 99 % confidence level from the area precision of eight sequential splitless injections of OFN (octafluoronaphthalene)

IDL measured using 100 fg injection, 1 ? L injection

Signal/noise sensitivity: 5000:1 with a 1μl injection of 1pg/μl OFN

Mass axis stability: < 0.10u over 48 hours

Massengenauigkeit +/- 0,005a

Scan rate: up to 20,000 rpm

Turbopump operation, incl. vacuum gauge, with software-controlled automatic rapid ventilation as well as corresponding calculations and display via the software

Dynamic Range 10E6

2 filaments for switching in case of defect of the active filament

Oil-free diaphragm backing pump (no scroll pump)

NIST Database

vacuum gauge

5 autosamplers for liquid injection in GC

Also suitable for the use of 2 injectors in the GC when retrofitting the 2nd channel. Type xyz robot

Feeding of samples incl. sample tray for approx. 160 sample vessels (2 ml each)

Full integration of the control software for the autosampler into the control software of the GC-MS system

An extension to other sample application techniques (headspace, pyrolysis, dynamic headspace to increase sensitivity, derivatization, overhead shakers for automated liquid-liquid extraction, sample preparation by means of solid phase extraction) must be possible modularly

It must be possible to edit running sequences and insert "urgent samples" at any time, even during operation

It must be possible to control two injectors

Parking station for syringe holders on the device

6 Control and evaluation unit - demand position -

Computer with current Windows operating system (at least Windows 10) for controlling the entire GC-MS-MS system

Mind. 24 Zoll TFT-Monitor

Software for control and evaluation must be compatible with the existing systems (Agilent Technologies - Masshunter Software); Same data format for flexible evaluation options

Control of the entire system (all modules including feeding system and autosampler) via only one method and one sequence list

Editing of running sequences must be possible

Control software of the current GC settings in real time, as well as fault diagnosis

Complete systems can be controlled via an Ethernet network

Current MS-Office in English

NIST database in the current version

7 Gerätehandbuch

Versions of the manuals, as far as possible, in German and electronic form

Manual of the gas chromatograph with operating instructions and application examples

Manual of the PTV injector with operating instructions and application examples

Manual of the MS-MS device with operating instructions and application examples

Manual of the autosampler with operating instructions as well as application examples for the injection of liquids

Manual and demonstrations on how to use the software

8 Installation

The system must be designed in such a way that the control PC can stand up to 15 m away from the device

It must be possible to connect the control PC via a network to another PC in another room for device operation and evaluation via remote access.

All software products on data carriers.

9 Briefing

User training for up to 5 people (approx. 2 days) for on-site training and handling of the device (in our own laboratory) The user training takes place directly after the installation and instruction of the devices by arrangement

Training of the software for 1st person at the manufacturer

Delivery of free place of use including transport, installation, commissioning and installation testing to the

Mortar mill RM 200 with mortar and pestle of the manufacturer RETSCH consisting of:

Position Manufacturer Number Description Number

1 20.455.0001 RM 200, with wiper made of PU, 230V, 50 Hz 1

2 02.460.0021 Tungsten carbide mortar for RM 200 1

3 02.461.0114 Tungsten carbide pestle for RM 200 1

All operating instructions and device manuals on data carriers or in the form of manuals in English, preferably in German.

The State Office for Nature, Environment and Consumer Protection of North Rhine-Westphalia intends to procure a system for semi-automated monitoring of the temperature and humidity of quality-relevant test equipment.

Only new devices are to be offered.

A detailed description of the devices must be attached to the offer in electronic form (CD-ROM or USB stick) in German and English. If a German description is not available, the claim is limited to the English version.

After the contract has been awarded and the order has been placed, detailed operating instructions in German and English in the form of manuals and in electronic form (e.g. CD-ROM or USB stick) must be supplied with the devices. If there are no detailed German versions, the claim is limited to the delivery of the English version.

The following requirements are minimum requirements

conditions

Recording and monitoring of parameters: temperature, humidity, expandable by the parameter CO2

Quality assurance: Application must be designed for an area accredited according to DIN EN ISO/IEC 17025 including tamper protection and electronic signatures

Software: Alarm management including escalation management, calibration management, graphical and tabular display of measurement data, individual limit values for alarm messages, user management (assignment of access, acknowledgment and processing rights), device management (creation of groups, spatial representation of devices/alarms)

Number of software licenses/users: unlimited number of users, up to 10 admins (options for entering and deleting sensors/devices, editing of user administration as well as full access, acknowledgment and editing rights)

Handling hardware and software: largely intuitive, the measurement data must be able to be monitored by various PCs integrated into the network

Measurement data storage: recording intervals in the range of 1 min to at least 24 h must be infinitely variable

Characteristics of the probes: digital probes, sensors Pt100 class A, between sleeve and cable at least protection class IP54, length of the measuring cable according to the local conditions

Number of temperature sensors:

Number of application accuracy at least

23 pcs cooling application (0.0 °C to 10.0 °C) ± (0.25 + 0.003 * | T|) °C

12 pcs deep-freeze application (-30.0 °C to 0.0 °C) ± (0.25 + 0.003 * | T|) °C

4 ultra-low temperature application (-90.0 °C to 0.0 °C) ± (0.25 + 0.003 * | T|) °C

1 pc ultra-low temperature application (-180.0 °C to 0.0 °C) ± (0.25 + 0.003 * | T|) °C

11 incubators (20.0 °C to 50.0 °C) ± (0.25 + 0.003 * | T|) °C

1 hot air sterilizer (150.0 °C to 200.0 °C) ± 1 °C at 170 °C

Additional 4 humidity/temperature cable probes (application at 20.0 °C to 50.0 °C and 0 %RH to 100 %RH; Accuracy at least ± 0.4 °C at +25 °C, ± 2.0 %RH at 0 %RH to 90 %RH at +25 °C and ± 0.03 %RH/K)

Calibration: when installing the devices, a DakkS calibration with at least 3 measuring points in the described scope of application of all measuring units for the parameters temperature and, if the sensor is available, humidity must be available or carried out directly by the provider

Data logger incl. communication modules (interchangeable) for all measuring units, at least 4 measurement channels must be available per data logger, 35 data logger units are to be offered

Features of the data loggers: one mounting unit supplied each, direct alarm via LED, battery-operated

If required in the future, it can be easily expanded by at least another 1,000 test equipment (at different locations)

Data security: Setting up a local internal office server, data export to CSV and PDF must be possible

Instruction/training of software and hardware

Type of communication of the modules: radio (must not interfere with the local WLAN), secure and efficient long-distance communication

Behavior in the event of a power failure: data caching (for at least 48 hours) and emergency alerting

Telephone support for technical questions

Commissioning:

- Installation of the software in consultation with the local IT

- Placement and assembly of the sensors

- Setting up the hardware and software (entering the measuring units, setting up the alarm management)

- Commissioning of the system

- Instruction in the system and the software

All components necessary for a functional system to ensure temperature monitoring on two different floors at one location

Installation, delivery and installation location

Delivery:

Delivery free of charge at the place of use including transport, installation, commissioning and installation testing

Delivery takes place during the usual office hours between 09.00 and 15.00.

The contractor shall coordinate the handover date with the client at least two weeks in advance. The contractor will be given the contact person when the order is placed. If a delivery cannot be made on the agreed date, the contractor is expressly prohibited from arbitrarily setting an alternative date. An alternative date must be agreed with the client.

After successful completion of the installation test and the instruction of the employees, the functional test is also completed and acceptance by the client is declared. From this point on, the warranty period / warranty period begins. Partial acceptances are not declared.

Delivery, commissioning and implementation of the user training by 01.11.2023 at the latest.

The State Office for Nature, Environment and Consumer Protection (LANUV) NRW intends to procure two mass spectrometers for the examination of samples for organic trace substances in water for timely water monitoring.

Geräteanforderungen

The mass spectrometers (MS) are to be integrated in combination with existing Agilent gas chromatographs of the type 7890A as a replacement for two older GC/MS (Varian, now Agilent) in two similarly designed online purge & trap GC/MS systems at the Bad Honnef and Kleve-Bimmen measuring stations.

The systems consist of:

- in-house sampler/autosampler (liquids) for time-controlled sampling from the pipelines of the measuring station,

- Purge & Trap concentrator from Teledyne/Tekmar (type Lumin in Bad Honnef, type Stratum in Kleve-Bimmen,

- Gerstel cold feed system (KAS) as Cryo Trap with modified firmware for real-time operation.

The gas chromatographs have so far been used for liquid injection with the KAS, which are now to be reinstalled at the free assembly stations. In addition, the side walls of the GCs must be prepared for use with the MS to be supplied. At the GC in Bad Honnef, a GCHI heater is to be dismantled in the right side wall.

To communicate between the GC/MS and the other components of the online system, only the TTL signals Ready and Start are required. The control of the KAS is independent of this. Carrier gas is supplied externally via the Purge & Trap concentrator.

For the operation of the entire systems, personal computers and software for the control of the GC/MS, for the recording and evaluation of the chromatograms (hereinafter referred to as workstations) are to be supplied.

1. Quadrupole mass spectrometer

- Turbopumpenbetrieb mind. 240 l/s (He)

- Ölfreie Vorvakuumpumpe

- Graphpack adapter for the GC/MS transferline

- EI ion source (70 eV) with double filament

- heated quadrupole

- Single mass resolution in full scan in the range from m/z 10 to 650 with a scan rate of min. 5 Hz

- SIM mode preferably quasi-parallel with fullscan in an experiment

2. Computer

- The recording of chromatograms must be fully controllable from a workstation with a Windows operating system - even under remote access to the computer in question. This is especially true for starting and stopping sequences.

- German keyboard, mouse, DVD, 24" monitor with 1920x1200 resolution

- Intel Core i7 (or better), min. 32 GB RAM, 500 GB SSD, 2x LAN, 6x USB

- free 2TB HDD NOT in RAID configuration,

- 3-4x RS232,

- Windows 10 prof., Office 2021

- For integration into the instrument network, the computer must provide a free Ethernet connection for connected devices

- At least one slot must be left free in the computer for a PCI card.

3. Instruments-Software (Workstation)

- The software must be able to programmatically execute series of analyses (sequences), whereby a special procedure (method) can be specified for each experiment. Alternatively, the system must be able to process several sequences one after the other using different methods.

- Tables with the analyses to be executed must be able to be imported from text files.

- The control of GC and MS must be stored in a single method file.

- The evaluation software must include automatic and manual peak detection, calibration and quantification taking into account internal standards, library search for mass spectra and an editor for creating libraries.

- Tables with analysis reports must be automatically generated and stored in text files or Excel files.

- The software must be able to export mass spectra to the NIST program for spectral comparison. In addition, you must be able to open the raw data files with AMDIS.

- An upgrade of the NIST library to the current version must be included.

- The documentation must contain an exact description of the format of the raw data, so that scans with retention times, mass numbers, intensities can be read by programmers.

Alternatively, a program must be supplied that stores the corresponding information completely in text files - preferably automatically as a post-run after each analysis.

- It must be possible to disable restrictions on the execution of the software for certain users.

- It must be possible to switch off all GLP functions.

4. Other

- The PC must be integrated into the laboratory network before installing the instrument.

- The installation of the workstation software must be demonstrated on site and documented in cooperation with the laboratory staff. This takes about half a day.

- Instruction in the use of tuning, method editor, starting and stopping sequences, evaluation, etc. on three days on site for three people

- Optional training for other people

5. Warranty

- Warranty for 24 months

6. Miscellaneous

All operating instructions and device manuals on data carriers or in the form of manuals in English, preferably in German.