St James’s hospital provides specialised molecular testing services using Next Generation Sequencing in five different national laboratories: Cancer Molecular Diagnostics (CMD) laboratory, Irish Mycobacterium Reference laboratory (IMRL), National MRSA Reference laboratory (NMRSARL), Haemostasis Molecular Diagnostics (HMD) laboratory and the Gonococcal Reference laboratory (GCRL). Scope Deliver a future-proofed solution for Molecular testing patient data, analysis and storage in a controlled and planned manner. A long term solution requires adding an additional layer of security to eliminate all locally based laboratory single points of failure, implement virtualised machines in the cloud environment, add additional data storage mechanisms (hot and cold storage) and manage costs accordingly and enhance the laboratory infrastructure further. We will expand on the backup processes for patient data, and expand on building the cloud environment and migration of the laboratory data (from sequencers) directly to the new cloud environment. Additional security protocols will be required and service maintenance arrangements adjusted to build resilience and capacity into the future. Allow for multiple virtual routers for individual laboratory connection between Genomics network and cloud environment (dedicated internet pipeline); Migrate current CMD server to cloud environment; Deliver hot storage (6 months of date) and cold (over 6 months) of data in the cloud and enable access of individual laboratory data by each laboratory team. Exception is NMRSARL and IMRL for dedicated hot storage only; Deliver access for multiple users to dedicated JSI software in the cloud environment for CMD laboratory; Remote access by laboratory team to the cloud environment; Dedicated back up expansion (as part of Phase1); Restoration plan for contingency events and restoring services to laboratories in event of system failures; Facilitate audits of the proposed solution (e.g. INAB, third party assessors); Procedure for unrestricted access of hot and cold storage. Audit of data access over the long term; Implement virtual machines for processing data from Genomics network equipment (sequencers etc.; quiet and burst timelines); Facilitate accessing all areas from dedicated SJH PCs. Web based access to Genomics network and cloud environment; New Cloud Linux (or comparable) environment solution to replace Linux standalone physical equipment (laptops, servers etc.) to run necessary software; Provide all relevant documentation in relation to solution processes in place, process maps, security information, data responsibilities, access policies, costing plans, audit and traceability; Options for implementing SQL database environments in the cloud environment to replace locally stored databases on-site; Assist with any training elements to the proposed solution for in-house personnel including our IT team at SJH.

St James’s hospital provides specialised molecular testing services using Next Generation Sequencing in five different national laboratories: Cancer Molecular Diagnostics (CMD) laboratory, Irish Mycobacterium Reference laboratory (IMRL), National MRSA Reference laboratory (NMRSARL), Haemostasis Molecular Diagnostics (HMD) laboratory and the Gonococcal Reference laboratory (GCRL). Scope Deliver a future-proofed solution for Molecular testing patient data, analysis and storage in a controlled and planned manner. A long term solution requires adding an additional layer of security to eliminate all locally based laboratory single points of failure, implement virtualised machines in the cloud environment, add additional data storage mechanisms (hot and cold storage) and manage costs accordingly and enhance the laboratory infrastructure further. We will expand on the backup processes for patient data, and expand on building the cloud environment and migration of the laboratory data (from sequencers) directly to the new cloud environment. Additional security protocols will be required and service maintenance arrangements adjusted to build resilience and capacity into the future. Allow for multiple virtual routers for individual laboratory connection between Genomics network and cloud environment (dedicated internet pipeline); Migrate current CMD server to cloud environment; Deliver hot storage (6 months of date) and cold (over 6 months) of data in the cloud and enable access of individual laboratory data by each laboratory team. Exception is NMRSARL and IMRL for dedicated hot storage only; Deliver access for multiple users to dedicated JSI software in the cloud environment for CMD laboratory; Remote access by laboratory team to the cloud environment; Dedicated back up expansion (as part of Phase1); Restoration plan for contingency events and restoring services to laboratories in event of system failures; Facilitate audits of the proposed solution (e.g. INAB, third party assessors); Procedure for unrestricted access of hot and cold storage. Audit of data access over the long term; Implement virtual machines for processing data from Genomics network equipment (sequencers etc.; quiet and burst timelines); Facilitate accessing all areas from dedicated SJH PCs. Web based access to Genomics network and cloud environment; New Cloud Linux (or comparable) environment solution to replace Linux standalone physical equipment (laptops, servers etc.) to run necessary software; Provide all relevant documentation in relation to solution processes in place, process maps, security information, data responsibilities, access policies, costing plans, audit and traceability; Options for implementing SQL database environments in the cloud environment to replace locally stored databases on-site; Assist with any training elements to the proposed solution for in-house personnel including our IT team at SJH.