With this contract file, whose conditions are established in the specifications, it is intended to cover the use of the drug included in the file to meet the clinical needs of Osakidetza patients and related centers and which are summarized in the report's memory.

Active substance: tacrolimus (DOE).

Amount of active substance: 0.5 mg, 1 mg, 3 mg and 5 mg.

Pharmaceutical form: extended-release capsules.

Packaging conditions: preferably unit dose.

Maximum unit price: EUR 17.73 / package of 30 capsules of 0.5 mg, EUR 31.26 / package of 30 capsules of 1 mg, EUR 60.87 / package of 60 capsules of 1 mg, EUR 91.49 / container of 30 capsules of 3 mg, 153.69 EUR / container of 30 capsules of 5 mg.

Number of units planned: 300 packs of 30 capsules of 0.5 mg, 2,000 packs of 30 capsules of 1 mg, 500 packs of 60 capsules of 1 mg, 100 packs of 30 capsules of 3 mg, 1,000 packs of 30 capsules 5 mg

Maximum estimated budget: EUR 261 113.00 (first year of contract).

Active substance: tacrolimus (DOE).

Amount of active substance: 0.75 mg, 1 mg and 4 mg.

Pharmaceutical form: prolonged release tablet.

Packaging conditions: preferably unit dose.

Maximum unit price: EUR 17.28 / pack of 30 tablets of 0.75 mg, EUR 23.04 / pack of 30 tablets of 1 mg, EUR 46.08 / pack of 60 tablets of 1 mg, EUR 92.16 / pack of 30 tablets of 4 mg.

Number of units planned: 300 packs of 30 tablets of 0.75 mg, 2,000 packs of 30 tablets of 1 mg, 500 packs of 60 tablets of 1 mg, 1,000 packs of 30 tablets of 4 mg.

Estimated maximum budget: 166 464.00 EUR (first year of contract).

Active substance: tacrolimus (DOE).

Amount of active substance: 5 mg.

Pharmaceutical form: blister.

Packaging conditions: unit dose.

Maximum unit price: EUR 185.74 / pack of 10 ampoules of 1 ml (5 mg / ml) (taxes not included).

Number of units planned: 150 packages of 10 ampoules of 1 ml (5 mg / ml) (first year of contract).

Estimated maximum budget: EUR 27 861.00 (first year of contract).