This is a joint European Public Tender of the AMC and VUMC; Amsterdam UMC (UMC)
For the hemato-oncological diagnostics and research laboratory in the Amsterdam UMC, we intend to purchase new spectral flow cytometers (3x), as the old equipment is outdated and no longer meets the current desired, and required by legislation, possibilities.
The purpose of the assignment is to select a single provider that can provide both locations with the required and desired spectral CE-IVD flow cytometer, with 16+ fluorescent channels given the necessary, and developing diagnostic panels in order to optimally provide diagnostic care. to be able to develop, innovate and implement.
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This tender concerns a joint procurement of the AMC and VUMC for the provision and maintenance of a 3-laser CE-IVD spectral flow cytometer for haemato-oncological diagnostics and research, including the necessary directly associated consumables for both site AMC and location. VUMC. Because of the merger, the laboratory hemato-oncology has started to jointly purchase equipment to be replaced with the aim of harmonizing laboratory diagnostics across both locations so that patients can be seen in both locations, without any differences in the laboratory results.
Purpose of the tender
The tender concerns the provision and maintenance of 3 minimum 3-laser CE-IVD spectral flow cytometers for hemato-oncological diagnostics and research. For this purpose, one provider is selected who can provide both location AMC and VUMC with the required and desired spectral CE-IVD flow cytometer that can simultaneously detect 16+ fluorochromes. This in view of the necessary, and under development, diagnostic panels in order to optimally develop, innovate and implement the diagnostic care provision.
Current situation
In the current situation, 3 laser BD FACSCanto flow cytometers is used. These are IVD 98/79/EC certified flow cytometers and can measure 8 colors in a conventional way that requires compensation between the different colors (fluorochromes). These flow cytometers are >10 years old and need replacement.
The development in the market of flow cytometers shows that it is possible, using spectral analysis, to measure 16 colors (and more) simultaneously and without compensation issues.
Expansion of the current 8 color panels to 16 colors or more is then possible and could lead to innovative and (qualitatively) improved panels for diagnostics. This can be considered, for example, high-dimensional panels for precious material (also in small volumes) such as liquors and other moisture.
Desired situation
To make the above developments possible, the AMC and VUMC are looking for a minimum 3-laser flow cytometer that can measure at least 16 colors simultaneously with spectral measurements without compensation issues. This is for the purpose of high-end hemato-oncological diagnostics. To this end, the flow cytometer must meet all the requirements set. It is important here that the flow cytometer can operate within the new IVDR 2017/746 European Directive, as all diagnostic provisions within hemato-oncological haematology must comply with these regulations. Therefore, the flow cytometer must be at least CE-IVD certified according to the European IVD 98/79/EC directive.
The desired system:
The desired system is a robust, reliable and stable spectral flow cytomer with 3 lasers (405 nm, 488 nm and 640 nm). The system must be able to detect at least 16 different fluorochromes in one panel/measurement.
Since the desired system will be used a very much, it is so important that the company has a (demonstrable) quality of support, minimizing downtime to maximize business operations.